Most Illustrious and most Excellent Lady, our very dear Sister,- Confident of the circumstance that there can be no more efficacious and salutary medicine for the indisposition from which you are at present suffering than the announcement of good and happy news, we advise you that at this very moment we have received sure tidings of the capture of Camerino. We beg that you will do honour to this message by an immediate improvement, and inform us of it, because, tormented as we are to know you so ill, nothing, not even this felicitous event, can suffice to afford us pleasure. We beg you also kindly to convey the present to the Illustrious Lord Don Alfonso, your husband and our beloved Brother-in-law, to whom we are not writing to-day.

What It Means

This is a placeholder explanation generated by the low-overhead model. It interprets "Most Illustrious and most Excellent Lady, our very dear Sister,- Confident of the circumstance that there can be no more efficacious and salutary medicine for the indisposition from which you are at present suffering than the announcement of good and happy news, we advise you that at this very moment we have received sure tidings of the capture of Camerino. We beg that you will do honour to this message by an immediate improvement, and inform us of it, because, tormented as we are to know you so ill, nothing, not even this felicitous event, can suffice to afford us pleasure. We beg you also kindly to convey the present to the Illustrious Lord Don Alfonso, your husband and our beloved Brother-in-law, to whom we are not writing to-day." in the context of "Cesare's letter to Lucrezia (July 1502), as quoted by Rafael Sabatini, 'The Life of Cesare Borgia', Chapter XIII: Urbino and Camerino." to mean that wisdom is timeless.